Timing hypothesis (menopausal hormone therapy)
Timing hypothesis (menopausal hormone therapy)
The Timing hypothesis refers to a theory in menopausal hormone therapy that suggests the timing of hormone replacement therapy (HRT) initiation can influence its effectiveness and potential risks. Pronounced as /ˈtaɪmɪŋ ˈhaɪpɒθɪsɪs/, the term is derived from the English words 'timing' and 'hypothesis', which mean 'the choice, judgment, or control of when something should be done' and 'a supposition or proposed explanation made on the basis of limited evidence as a starting point for further investigation', respectively.
Overview
The Timing Hypothesis proposes that the effects of HRT are modulated by the time of initiation relative to menopause. According to this hypothesis, early initiation of HRT, close to the onset of menopause, is associated with beneficial effects, while late initiation, several years after menopause, may be associated with risks.
Related Terms
- Menopause: The natural cessation of menstruation that usually occurs between the ages of 45 and 55.
- Hormone Replacement Therapy (HRT): A treatment used to augment the body's natural hormone levels, either in the form of estrogen-alone therapy (ET), or as estrogen with progesterone therapy (EPT).
- Estrogen: A group of hormones that play an essential role in the growth and development of female sexual characteristics and the reproductive process.
- Progesterone: A hormone released by the corpus luteum that stimulates the uterus to prepare for pregnancy.
See Also
External links
- Medical encyclopedia article on Timing hypothesis (menopausal hormone therapy)
- Wikipedia's article - Timing hypothesis (menopausal hormone therapy)
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