Thyrotropin-releasing hormone
Thyrotropin-releasing hormone
Thyrotropin-releasing hormone (TRH), also known as thyrotropin-releasing factor (TRF), is a hypothalamic hormone responsible for the stimulation of thyrotropin secretion by the pituitary gland. Pronounced as "thy-ro-tro-pin-re-leas-ing hor-mone", the term is derived from the Greek words 'thyreos' meaning shield, 'tropos' meaning turning, 'rhein' meaning to flow, and 'hormao' meaning to excite or arouse.
Function
TRH is a tripeptide hormone produced and released by the hypothalamus. It stimulates the pituitary gland to release thyroid-stimulating hormone (TSH), which in turn stimulates the thyroid gland to produce and release thyroid hormones.
Clinical significance
Abnormal levels of TRH can lead to a variety of medical conditions, including hyperthyroidism, hypothyroidism, and certain types of pituitary tumors.
Related terms
- Thyrotropin: A hormone secreted by the pituitary gland that regulates the production of thyroid hormones.
- Thyroid-stimulating hormone: A hormone that stimulates the thyroid gland to produce thyroid hormones.
- Thyroid hormones: Hormones produced by the thyroid gland that regulate metabolism.
See also
External links
- Medical encyclopedia article on Thyrotropin-releasing hormone
- Wikipedia's article - Thyrotropin-releasing hormone
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