Sparsentan
Sparsentan
Sparsentan (pronunciation: spar-SEN-tan) is a pharmaceutical drug used in the treatment of certain kidney diseases. It is a dual-acting angiotensin receptor blocker and endothelin receptor antagonist.
Etymology
The name "Sparsentan" is derived from the Latin word "sparsus", meaning scattered or dispersed, and "entan", a common suffix in drug nomenclature indicating its action as an antagonist.
Pharmacology
Sparsentan works by blocking the actions of both angiotensin II and endothelin-1, two hormones that can contribute to kidney damage in certain diseases. By blocking these hormones, Sparsentan can help to protect the kidneys and slow the progression of disease.
Clinical Use
Sparsentan is currently being investigated for use in the treatment of Focal Segmental Glomerulosclerosis (FSGS) and IgA nephropathy, two types of kidney disease that can lead to end-stage renal disease.
Related Terms
- Angiotensin II
- Endothelin-1
- Focal Segmental Glomerulosclerosis
- IgA nephropathy
- End-stage renal disease
External links
- Medical encyclopedia article on Sparsentan
- Wikipedia's article - Sparsentan
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