Retinoic acid receptor alpha gene
| Retinoic acid receptor alpha gene | |
|---|---|
| Term | Retinoic acid receptor alpha gene |
| Short definition | Retinoic acid receptor alpha gene - (pronounced) (REH-tih-NOH-ik A-sid reh-SEP-ter AL-fuh jeen) gene that makes a protein that controls the activity of certain genes that help white blood cells to mature. Mutations (changes) in the retinoic acid receptor alpha gene can occur when a piece of the chromosome that contains the retinoic acid receptor alpha gene breaks off and joins a gene called PML on another chromosome. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
Retinoic acid receptor alpha gene - (pronounced) (REH-tih-NOH-ik A-sid reh-SEP-ter AL-fuh jeen) gene that makes a protein that controls the activity of certain genes that help white blood cells to mature. Mutations (changes) in the retinoic acid receptor alpha gene can occur when a piece of the chromosome that contains the retinoic acid receptor alpha gene breaks off and joins a gene called PML on another chromosome. These changes can cause too many immature white blood cells to build up in the blood and bone marrow. This can lead to an aggressive (rapidly growing) type of acute myeloid leukemia called acute promyelocytic leukemia. The protein made by the retinoic acid receptor alpha gene is a type of transcription factor. Also called RARA gene
External links
- Medical encyclopedia article on Retinoic acid receptor alpha gene
- Wikipedia's article - Retinoic acid receptor alpha gene
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