Respiratory burst
Respiratory burst
Respiratory burst (pronunciation: /rɪˈspɪrətɔːri bɜːrst/) is a process in which phagocytes produce reactive oxygen species (ROS) to kill invading microorganisms.
Etymology
The term "respiratory burst" comes from the rapid uptake of oxygen observed when these cells are stimulated, which is reminiscent of a sudden burst of respiration.
Process
During the respiratory burst, the NADPH oxidase complex assembles in the phagosome membrane and begins to produce superoxide, a reactive oxygen species. This superoxide can be converted into other reactive oxygen species, such as hydrogen peroxide and hydroxyl radicals, which can damage and kill the invading microorganism.
Related Terms
See Also
References
External links
- Medical encyclopedia article on Respiratory burst
- Wikipedia's article - Respiratory burst
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