Reactogenicity
Reactogenicity (pronounced: ree-ak-toh-jen-iss-ity) is a term used in vaccinology to describe the property of a vaccine that leads to adverse reactions among those who receive it. The term is derived from the Latin reactio meaning "a reaction" and the Greek -genēs meaning "born of, produced by".
Definition
Reactogenicity refers to the physical manifestation of the inflammatory response to vaccination, and it is often used as a measure of the severity of adverse reactions that can be directly attributed to the vaccine itself. These reactions can range from mild, such as a sore arm or low-grade fever, to severe, such as anaphylaxis.
Related Terms
- Adverse event following immunization (AEFI): An adverse event following immunization is any untoward medical occurrence which follows immunization and which does not necessarily have a causal relationship with the usage of the vaccine. The adverse event may be any unfavorable or unintended sign, abnormal laboratory finding, symptom or disease.
- Immunogenicity: Immunogenicity is the ability of a particular substance, such as an antigen or epitope, to provoke an immune response in the body of a human or animal.
- Vaccine: A vaccine is a biological preparation that provides active acquired immunity to a particular infectious disease.
- Vaccinology: Vaccinology is the science of vaccines, it involves continuous research and development, as well as the production and application of vaccines.
See Also
External links
- Medical encyclopedia article on Reactogenicity
- Wikipedia's article - Reactogenicity
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