RFLP
RFLP
RFLP (pronounced ar-eff-el-pee), or Restriction Fragment Length Polymorphism, is a technique that exploits variations in homologous DNA sequences. It refers to a difference in homologous DNA sequences that can be detected by the presence of fragments of different lengths after digestion of the DNA samples with specific restriction endonuclease enzymes.
Etymology
The term "RFLP" is an acronym derived from Restriction Fragment Length Polymorphism. The term was first coined in the early 1980s when scientists began to explore the variations in DNA sequences among individuals.
Related Terms
- DNA: Deoxyribonucleic acid, the molecule that carries genetic information in all living organisms and many viruses.
- Restriction endonuclease enzymes: Enzymes that cut DNA at specific sequences.
- Polymorphism (biology): The occurrence of two or more clearly different forms, also referred to as alternative phenotypes, in the population of a species.
- Genetic variation: Variation in alleles of genes that occurs both within and among populations.
- Molecular genetics: The field of biology and genetics that studies the structure and function of genes at a molecular level.
See Also
- PCR: Polymerase Chain Reaction, a method widely used in molecular biology to make copies of a specific DNA segment.
- Genetic mapping: The process of determining the locus for a particular biological trait.
- DNA sequencing: The process of determining the nucleic acid sequence – the order of nucleotides in DNA.
External links
- Medical encyclopedia article on RFLP
- Wikipedia's article - RFLP
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski