Protein-losing enteropathy

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Protein-losing enteropathy (pronunciation: proh-teen loh-zing en-ter-op-uh-thee) is a medical condition characterized by the loss of serum proteins into the intestine.

Etymology

The term "Protein-losing enteropathy" is derived from the Greek words "proteios" meaning "of the first quality", "enteron" meaning "intestine", and "pathos" meaning "suffering".

Definition

Protein-losing enteropathy is a condition that occurs when albumin and other serum proteins are lost from the body through the gastrointestinal tract. This can lead to hypoproteinemia, a condition characterized by abnormally low levels of protein in the blood.

Causes

The condition can be caused by a variety of diseases that affect the lining of the intestines, including inflammatory bowel disease, celiac disease, and intestinal lymphangiectasia. It can also occur as a complication of certain surgeries, such as Fontan procedure.

Symptoms

Symptoms of protein-losing enteropathy can include edema, ascites, and malnutrition. In severe cases, it can lead to anemia and immune system dysfunction due to loss of immunoglobulins.

Diagnosis

Diagnosis of protein-losing enteropathy typically involves a combination of blood tests, stool tests, and imaging studies. The alpha-1 antitrypsin clearance test is often used to confirm the diagnosis.

Treatment

Treatment of protein-losing enteropathy involves addressing the underlying cause of the protein loss. This may involve medication, dietary changes, or in some cases, surgery.

See also

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