Propionibacterium acnes
Propionibacterium acnes
Propionibacterium acnes (pronounced: pro-pee-oh-ni-bak-teer-ee-um ak-neez) is a gram-positive human skin commensal that prefers anaerobic growth conditions. It is primarily associated with the skin condition acne vulgaris.
Etymology
The name "Propionibacterium" is derived from the Greek words "propios" meaning "pertaining to fat" and "bacterium" meaning "small rod". This is in reference to the bacterium's ability to produce propionic acid. The term "acnes" is derived from the Latin word "acne" which means "a skin eruption".
Description
Propionibacterium acnes is a rod-shaped, non-spore-forming, and non-motile bacterium. It is part of the normal flora of the human skin and is particularly prevalent in areas with large numbers of sebaceous glands, such as the face and upper part of the chest. While it is generally harmless, under certain conditions it can cause acne vulgaris, a common skin condition characterized by pimples and inflammation.
Pathogenesis
The pathogenesis of Propionibacterium acnes in acne vulgaris is not fully understood. However, it is believed to involve the bacterium's ability to trigger an immune response, leading to inflammation. It is also known to produce enzymes that can damage the skin and hair follicles, leading to the formation of comedones, or acne lesions.
Treatment
Treatment for Propionibacterium acnes typically involves the use of topical or oral antibiotics, such as erythromycin or tetracycline. In some cases, isotretinoin, a retinoid, may be used. It is also important to maintain good skin hygiene to prevent the overgrowth of the bacterium.
Related Terms
External links
- Medical encyclopedia article on Propionibacterium acnes
- Wikipedia's article - Propionibacterium acnes
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