Promyelocytic leukemia gene
| Promyelocytic leukemia gene | |
|---|---|
| Term | Promyelocytic leukemia gene |
| Short definition | promyelocytic leukemia gene - (pronounced) (proh-MY-eh-loh-SIH-tik loo-KEE-mee-uh jeen) gene that makes a protein that helps control cell growth and division. Mutations (changes) in the promyelocytic leukemia gene can occur when a piece of the chromosome that contains the promyelocytic leukemia gene breaks off and joins a gene called RARA on another chromosome. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
promyelocytic leukemia gene - (pronounced) (proh-MY-eh-loh-SIH-tik loo-KEE-mee-uh jeen) gene that makes a protein that helps control cell growth and division. Mutations (changes) in the promyelocytic leukemia gene can occur when a piece of the chromosome that contains the promyelocytic leukemia gene breaks off and joins a gene called RARA on another chromosome. These changes can cause too many immature white blood cells to build up in the blood and bone marrow. This can lead to an aggressive (rapidly growing) type of acute myeloid leukemia called acute promyelocytic leukemia. The promyelocytic leukemia gene is a type of tumor suppressor gene. Also called PML gene
External links
- Medical encyclopedia article on Promyelocytic leukemia gene
- Wikipedia's article - Promyelocytic leukemia gene
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