Primary fibrinogenolysis
Primary fibrinogenolysis
Primary fibrinogenolysis (pronunciation: pri·ma·ry | \ ˈprī-ˌmer-ē, -mə-rē \ fib·ri·no·gen·ol·y·sis | \ ˌfi-brə-nō-jə-ˈnä-lə-səs \) is a rare hematological disorder characterized by the abnormal breakdown of fibrinogen, a protein involved in blood clotting. The etymology of the term comes from the Latin "primarius" meaning "first" and the Greek "fibrinogen" meaning "producer of fibrin" and "lysis" meaning "loosening or dissolving".
Symptoms and Diagnosis
Symptoms of primary fibrinogenolysis can include bleeding, bruising, and in severe cases, disseminated intravascular coagulation (DIC). Diagnosis typically involves blood tests to measure fibrinogen levels and clotting times.
Causes and Treatment
The exact cause of primary fibrinogenolysis is unknown, but it is thought to be related to an overactive fibrinolytic system. Treatment typically involves addressing the underlying cause, if known, and may include antifibrinolytic medications to slow the breakdown of fibrinogen.
Related Terms
- Fibrinogen: A protein in the blood that helps form clots to stop bleeding.
- Fibrinolysis: The process of breaking down fibrin, a protein that forms a mesh-like structure to help form a blood clot.
- Disseminated intravascular coagulation (DIC): A condition in which small blood clots develop throughout the bloodstream, blocking small blood vessels.
See Also
External links
- Medical encyclopedia article on Primary fibrinogenolysis
- Wikipedia's article - Primary fibrinogenolysis
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