Prenylamine
Prenylamine
Prenylamine (pronunciation: preh-nil-a-meen) is a medication that was primarily used as a vasodilator in the treatment of angina pectoris, a condition characterized by chest pain due to reduced blood flow to the heart.
Etymology
The term "Prenylamine" is derived from the chemical structure of the drug, which contains a prenyl group. A prenyl group is a hydrocarbon group derived from isoprene. The suffix "-amine" refers to the presence of an amino group in the molecule.
Pharmacology
Prenylamine acts by inhibiting the uptake of calcium ions into the heart muscle cells, thereby relaxing the blood vessels and increasing the supply of blood and oxygen to the heart. This helps to alleviate the symptoms of angina pectoris.
Related Terms
- Vasodilator: A type of medication that dilates (widens) blood vessels to improve blood flow.
- Angina pectoris: A type of chest pain caused by reduced blood flow to the heart.
- Calcium ions: Electrically charged particles of calcium, a mineral that is essential for the normal functioning of the body.
- Isoprene: A common organic compound that is the basis for many natural and synthetic polymers.
Side Effects
Like all medications, Prenylamine can cause side effects. These may include dizziness, headache, flushing, and stomach upset. If these effects persist or worsen, medical attention should be sought.
Withdrawal
Prenylamine was withdrawn from the market worldwide in 1988 due to concerns about its potential to cause serious cardiac arrhythmias.
External links
- Medical encyclopedia article on Prenylamine
- Wikipedia's article - Prenylamine
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