Pregnenedione
Pregnenedione
Pregnenedione (pronounced: preɡ-nen-e-di-on) is a steroid metabolite that is derived from progesterone. It is a precursor to several other important hormones in the body, including cortisol, aldosterone, and androgens.
Etymology
The term "Pregnenedione" is derived from the word "pregnane", which is a term used in organic chemistry to refer to a class of steroids. The suffix "-dione" is used in chemistry to denote a compound containing two ketone groups.
Function
Pregnenedione is a key intermediate in the biosynthesis of many important hormones. It is converted from progesterone by the enzyme 3β-hydroxysteroid dehydrogenase, and can then be further converted into other hormones such as cortisol, aldosterone, and androgens. These hormones play crucial roles in a variety of physiological processes, including metabolism, immune response, and blood pressure regulation.
Related Terms
- Steroid: A type of organic molecule that is characterized by a specific arrangement of carbon atoms in a four-ring structure.
- Progesterone: A hormone that plays a key role in the menstrual cycle and in maintaining the early stages of pregnancy.
- Cortisol: A hormone that helps the body respond to stress.
- Aldosterone: A hormone that helps regulate the balance of water and electrolytes in the body.
- Androgens: A group of hormones that play a role in male traits and reproductive activity.
- 3β-hydroxysteroid dehydrogenase: An enzyme that catalyzes the conversion of progesterone to pregnenedione.
- Biosynthesis: The production of complex molecules within living organisms or cells.
External links
- Medical encyclopedia article on Pregnenedione
- Wikipedia's article - Pregnenedione
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