Pleomorphic adenoma
Pleomorphic adenoma (pronunciation: plee-oh-MOR-fik ad-uh-NOH-muh) is a benign tumor that originates from the salivary glands. It is the most common type of salivary gland tumor and it primarily affects the parotid gland.
Etymology
The term "pleomorphic" is derived from the Greek words "pleio" meaning more, and "morphe" meaning form, referring to the tumor's ability to appear in various shapes and sizes under a microscope. "Adenoma" is derived from the Greek words "aden" meaning gland, and "-oma" meaning tumor or mass.
Characteristics
Pleomorphic adenomas are characterized by their slow growth and encapsulated nature. They are composed of a mixture of glandular epithelial cells and myoepithelial cells, which contribute to their pleomorphic appearance. Despite being benign, these tumors have the potential to become malignant, a condition known as carcinoma ex pleomorphic adenoma.
Symptoms
The most common symptom of a pleomorphic adenoma is a painless, slow-growing mass in the area of the salivary glands. Other symptoms may include facial nerve palsy, difficulty swallowing, and changes in voice.
Diagnosis
Diagnosis of pleomorphic adenoma typically involves a physical examination, imaging studies such as CT or MRI, and a biopsy for histopathological examination.
Treatment
The primary treatment for pleomorphic adenoma is surgical removal of the tumor. In some cases, radiation therapy may be used as an adjunct to surgery.
Related Terms
- Benign tumor
- Salivary gland
- Parotid gland
- Epithelial cells
- Myoepithelial cells
- Carcinoma ex pleomorphic adenoma
- CT
- MRI
External links
- Medical encyclopedia article on Pleomorphic adenoma
- Wikipedia's article - Pleomorphic adenoma
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