Platypnea-orthodeoxia syndrome
Platypnea-orthodeoxia syndrome (pronunciation: plat-ip-nee-uh or-tho-dee-ox-ee-uh syndrome) is a rare medical condition characterized by dyspnea (shortness of breath) that is aggravated by standing or sitting upright and is relieved by lying down, associated with hypoxemia (low blood oxygen levels).
Etymology
The term "Platypnea-orthodeoxia syndrome" is derived from the Greek words "platys" meaning flat, "pnoia" meaning breath, "orthos" meaning straight, and "deoxia" referring to the lack of oxygen.
Symptoms
The primary symptom of Platypnea-orthodeoxia syndrome is dyspnea that worsens upon standing or sitting and improves when lying down. Other symptoms may include cyanosis (bluish discoloration of the skin due to low oxygen), tachycardia (rapid heart rate), and fatigue.
Causes
The exact cause of Platypnea-orthodeoxia syndrome is unknown, but it is often associated with conditions that alter the normal anatomical relationship between the heart and the lungs, such as atrial septal defect and pulmonary arteriovenous malformation.
Diagnosis
Diagnosis of Platypnea-orthodeoxia syndrome is typically made based on the patient's symptoms and confirmed through pulse oximetry and arterial blood gas tests. Additional diagnostic tests may include echocardiography and computed tomography (CT) scans.
Treatment
Treatment for Platypnea-orthodeoxia syndrome is aimed at correcting the underlying cause, if known. This may involve surgical repair of an atrial septal defect or treatment of pulmonary arteriovenous malformation. In some cases, supplemental oxygen may be required.
See also
External links
- Medical encyclopedia article on Platypnea-orthodeoxia syndrome
- Wikipedia's article - Platypnea-orthodeoxia syndrome
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