Phenibut
Phenibut
Phenibut (pronounced: /ˈfɛnɪbʌt/), also known as β-Phenyl-γ-aminobutyric acid is a central nervous system depressant with anxiolytic and sedative effects. It is used in Russia as a pharmaceutical drug to treat a wide range of ailments including post-traumatic stress disorder, depression, asthenia, insomnia, alcoholism, stuttering, and vestibular disorders.
Etymology
The name "Phenibut" is derived from its chemical name, β-Phenyl-γ-aminobutyric acid. The prefix "Pheni-" comes from the chemical structure of the compound, which includes a phenyl ring. The "-but" part of the name refers to the presence of a four-carbon butyric acid chain.
Pharmacology
Phenibut acts as a full agonist of the GABA receptors, specifically at the GABAB subtype, and has some effect at the GABAA subtype. It also stimulates dopamine receptors and has an antagonistic effect on β-phenethylamine (PEA), a naturally occurring trace amine neuromodulator.
Related Terms
- GABA: Gamma-Aminobutyric acid, a naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity.
- Anxiolytic: A medication or other intervention that inhibits anxiety.
- Sedative: A substance that induces sedation by reducing irritability or excitement.
- Asthenia: Weakness. Lack of energy and strength. Loss of strength. The word asthenia is not much used in medicine today, although it is a part of myasthenia, a loss of muscle strength, as in myasthenia gravis.
- Vestibular Disorders: Disorders of the body's balance (vestibular) system in the inner ear.
External links
- Medical encyclopedia article on Phenibut
- Wikipedia's article - Phenibut
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