Phase

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Phase (Medicine)

Phase (/feɪz/; from the Ancient Greek: φάσις, phásis, 'appearance') is a term used in various contexts within the field of medicine and healthcare.

Definition

In a medical context, a phase often refers to a distinct period or stage in a process of change or development, such as the phases of clinical trials or the phases of disease progression.

Etymology

The term 'phase' originates from the Ancient Greek word phásis, which means 'appearance'. It was first used in the English language in the early 19th century to describe the different stages of the moon. The term was later adopted by the medical community to describe the different stages of disease progression and clinical trials.

Related Terms

  • Clinical trial: A research investigation in which people volunteer to test new treatments, interventions or tests as a means to prevent, detect, treat or manage various diseases or medical conditions.
  • Disease progression: The process by which a disease advances in severity over time.
  • Phase I trial: The first stage in the testing of a new drug or treatment in humans, designed to assess safety and dosage.
  • Phase II trial: The second stage of testing, which assesses the efficacy of a drug or treatment and further evaluates its safety.
  • Phase III trial: The third stage of testing, which involves randomized and blind testing in several hundred to several thousand patients to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
  • Phase IV trial: Also known as post-marketing surveillance trial, it involves the safety surveillance and ongoing technical support of a drug after it receives permission to be sold.

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