Paralog

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Paralog

Paralog (/pærəlɔːg/), from the Greek words para meaning "beside" and logos meaning "word", is a term used in Genetics to refer to one of two or more genes that are derived from the same ancestral gene through gene duplication events.

Paralogs typically have similar sequences and are often found within the same organism due to duplication events. However, over time, paralogs can acquire new functions. This is known as Neofunctionalization.

Related Terms

  • Ortholog: An ortholog is a gene in different species that evolved from a common ancestral gene by Speciation. Orthologs retain the same function in the course of evolution.
  • Homologous genes: Homologous genes are genes in the same or different species that share a common ancestral DNA sequence. They can be either orthologs or paralogs.
  • Gene duplication: Gene duplication is a major mechanism through which new genetic material is generated during molecular evolution. It can be defined as any duplication of a region of DNA that contains a gene.
  • Neofunctionalization: Neofunctionalization is the process by which a gene, following a duplication event, acquires a new function.

See Also

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