PTPRC
PTPRC
PTPRC (pronounced as P-T-P-R-C), also known as Protein Tyrosine Phosphatase Receptor Type C, is a protein that in humans is encoded by the PTPRC gene.
Etymology
The term PTPRC is an acronym derived from the full name of the protein it represents, Protein Tyrosine Phosphatase Receptor Type C. The term is used in the field of Genetics and Molecular Biology to denote this specific protein.
Definition
PTPRC is a member of the Protein Tyrosine Phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Function
This PTP is expressed in hematopoietic cells and has been implicated in the regulation of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various downstream signaling pathways.
Related Terms
- Protein Tyrosine Phosphatase (PTP): A type of protein that removes phosphate groups from phosphorylated tyrosine residues on proteins.
- Hematopoietic cells: The blood cells that give rise to all other blood cells through the process of haematopoiesis.
- Antigen receptor: A molecule found on the surface of T cells, or in some cases, B cells, that recognizes and binds to antigens.
- Oncogenic transformation: The process by which healthy cells are transformed into cancer cells.
See Also
- PTPRC gene
- Protein Tyrosine Phosphatase
- Hematopoietic cells
- Antigen receptor
- Oncogenic transformation
External links
- Medical encyclopedia article on PTPRC
- Wikipedia's article - PTPRC
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