PML gene
PML gene | |
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Term | PML gene |
Short definition | PML gene - gene that makes a protein that helps control cell growth and division. Mutations (changes) in the PML gene can occur when a piece of the chromosome that contains the PML gene breaks off and joins a gene called RARA on another chromosome. |
Type | Cancer terms |
Specialty | Oncology |
Language | English |
Source | NCI |
Comments |
PML gene - gene that makes a protein that helps control cell growth and division. Mutations (changes) in the PML gene can occur when a piece of the chromosome that contains the PML gene breaks off and joins a gene called RARA on another chromosome. These changes can cause too many immature white blood cells to build up in the blood and bone marrow. This can lead to an aggressive (rapidly growing) type of acute myeloid leukemia called acute promyelocytic leukemia. The PML gene is a type of tumor suppressor gene. Also called promyelocytic leukemia gene
External links
- Medical encyclopedia article on PML gene
- Wikipedia's article - PML gene
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