PCA3
PCA3
PCA3 (pronounced P-C-A-three), also known as Prostate Cancer Antigen 3, is a gene that is overexpressed in prostate cancer cells, making it a useful biomarker for the disease.
Pronunciation
PCA3 is pronounced as "P-C-A-three".
Etymology
The term PCA3 is an acronym derived from Prostate Cancer Antigen 3. It was named for its role in prostate cancer detection.
Definition
PCA3 is a non-coding RNA that is highly specific to prostate cancer. It is used as a biomarker in a urine test to help determine the need for repeat prostate biopsies in men who have had a previous negative biopsy.
Related Terms
- Prostate Cancer: A form of cancer that develops in the prostate, a gland in the male reproductive system.
- Gene: A unit of heredity which is transferred from a parent to offspring and is held to determine some characteristic of the offspring.
- RNA: Ribonucleic acid, a nucleic acid present in all living cells. Its principal role is to act as a messenger carrying instructions from DNA for controlling the synthesis of proteins.
- Biomarker: A measurable indicator of some biological state or condition.
- Biopsy: An examination of tissue removed from a living body to discover the presence, cause, or extent of a disease.
External links
- Medical encyclopedia article on PCA3
- Wikipedia's article - PCA3
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