Oleandrin
Oleandrin (pronounced: oh-lee-AN-drin) is a toxic cardiac glycoside found in the Oleander plant, scientifically known as Nerium oleander.
Etymology
The term "Oleandrin" is derived from the plant's genus name Oleander, which is a shrub native to northern Africa, the eastern Mediterranean basin, and Southeast Asia.
Chemical Structure and Properties
Oleandrin is a type of cardiac glycoside, a class of organic compounds that have a direct effect on the heart muscle's contractility. It is structurally similar to digoxin, another cardiac glycoside used in the treatment of heart failure and arrhythmias.
Toxicity
Oleandrin is highly toxic and can cause severe vomiting, slow heart rate, and can even be lethal in high doses. It is one of the compounds responsible for the toxicity of the Oleander plant.
Medical Use
Despite its toxicity, oleandrin has been studied for potential use in cancer treatment. Some research suggests that it may have anti-cancer properties, but these findings are still preliminary and more research is needed.
Related Terms
External links
- Medical encyclopedia article on Oleandrin
- Wikipedia's article - Oleandrin
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