Nodular vasculitis
Nodular Vasculitis
Nodular vasculitis (pronunciation: /ˈnɒdjʊlər vaskjʊˈlaɪtɪs/) is a chronic, recurrent, inflammatory condition that primarily affects the blood vessels in the subcutaneous fat. It is characterized by the presence of painful, erythematous nodules on the lower extremities.
Etymology
The term "nodular" is derived from the Latin word "nodulus", meaning a small node, and "vasculitis" comes from the Latin "vasculum" meaning little vessel and the Greek "-itis" denoting inflammation. Thus, nodular vasculitis can be understood as inflammation of small vessels forming nodules.
Symptoms
The primary symptom of nodular vasculitis is the presence of painful, erythematous nodules, typically located on the lower extremities. Other symptoms may include fever, malaise, and weight loss.
Causes
The exact cause of nodular vasculitis is unknown. However, it is often associated with conditions such as tuberculosis, sarcoidosis, and autoimmune diseases.
Diagnosis
Diagnosis of nodular vasculitis is typically made based on clinical presentation and histopathological examination of a skin biopsy. Other diagnostic tests may include blood tests, imaging studies, and cultures to rule out infectious causes.
Treatment
Treatment of nodular vasculitis typically involves the use of anti-inflammatory medications, such as corticosteroids, and immunosuppressive drugs. In cases associated with tuberculosis, anti-tubercular therapy is also required.
Prognosis
The prognosis of nodular vasculitis is generally good with appropriate treatment. However, the condition can be recurrent and may require long-term management.
Related Terms
External links
- Medical encyclopedia article on Nodular vasculitis
- Wikipedia's article - Nodular vasculitis
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