Nimesulide
Nimesulide
Nimesulide (pronounced /niːmɛsjuːlaɪd/) is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old.
Etymology
The term "Nimesulide" is derived from the French word 'Nimes', referring to the city in France where it was first synthesized, and 'sulide', a common suffix for sulphonanilide derivatives.
Pharmacology
Nimesulide works by blocking the action of a substance in the body called cyclooxygenase-2 (COX-2). COX-2 is involved in the production of irritants in the body in response to disease. By blocking the action of COX-2, nimesulide reduces the symptoms of inflammation, such as pain and swelling.
Side Effects
Common side effects of Nimesulide include stomach pain, nausea, diarrhea, and skin rash. In rare cases, it can cause serious side effects like liver damage, severe skin reactions, and allergic reactions.
Related Terms
See Also
External links
- Medical encyclopedia article on Nimesulide
- Wikipedia's article - Nimesulide
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