NephroCheck
NephroCheck
NephroCheck (/ˈnɛfroʊˌtʃɛk/) is a diagnostic test used to assess the risk of acute kidney injury (AKI) in critically ill patients.
Etymology
The term "NephroCheck" is derived from the Greek word "nephros" meaning kidney, and the English word "check", implying a test or examination.
Usage
NephroCheck measures the levels of two biomarkers, insulin-like growth factor-binding protein 7 (IGFBP7) and tissue inhibitor of metalloproteinases-2 (TIMP-2), in the urine. These biomarkers are cell-cycle arrest proteins that increase in response to kidney stress. High levels of these biomarkers indicate a higher risk of developing AKI.
Related Terms
- Acute Kidney Injury: A sudden episode of kidney failure or kidney damage that happens within a few hours or a few days.
- Biomarker: A measurable substance in an organism whose presence is indicative of some phenomenon such as disease, infection, or environmental exposure.
- Insulin-like growth factor-binding protein 7: A protein that in humans is encoded by the IGFBP7 gene.
- Tissue inhibitor of metalloproteinases-2: A protein that in humans is encoded by the TIMP2 gene.
See Also
External links
- Medical encyclopedia article on NephroCheck
- Wikipedia's article - NephroCheck
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