Myeloproliferative neoplasms

Myeloproliferative Neoplasms (MPNs) (/maɪˌiːloʊprəˈlɪfərətɪv ˈniːəˌplæzəmz/) are a group of diseases of the blood and bone marrow in which the body makes too many red blood cells, white blood cells, or platelets.

Etymology

The term "Myeloproliferative" is derived from "myelo-" meaning marrow, and "proliferative" referring to cell multiplication. "Neoplasms" refers to new, often abnormal, growth of tissue.

Types of MPNs

There are several types of MPNs, including:

• Polycythemia Vera (PV)
• Essential Thrombocythemia (ET)
• Primary Myelofibrosis (PMF)
• Chronic Myelogenous Leukemia (CML)

Symptoms

Symptoms of MPNs can vary widely, depending on the specific type of disorder. They may include fatigue, shortness of breath, easy bruising or bleeding, and frequent infections.

Diagnosis

Diagnosis of MPNs typically involves blood tests, bone marrow tests, and genetic testing.

Treatment

Treatment for MPNs depends on the specific type of disorder and may include medication, blood drawing (phlebotomy), radiation therapy, or stem cell transplant.

Related Terms

• Hematology - the study of blood, blood-forming organs, and blood diseases.
• Oncology - the study of cancer and tumors, including the diagnosis, treatment, and prevention of cancer.

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