Milan criteria

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Milan Criteria

The Milan Criteria (pronounced: mi-lan kri-te-ri-a) is a set of guidelines used in the field of Hepatology to determine the suitability of a patient with Hepatocellular carcinoma (HCC) for a Liver transplantation. These criteria were established in Milan, Italy, hence the name.

Etymology

The term "Milan Criteria" is derived from the city of Milan in Italy, where the criteria were first established in 1996 by a team of doctors at the University of Milan. The word "criteria" is a plural form of the Latin word "criterium", which means a standard or rule for judging something.

Definition

According to the Milan Criteria, a patient with HCC is considered suitable for a liver transplant if they have:

  • A single tumor that is less than or equal to 5 cm in diameter, or
  • Up to three tumors, none of which are more than 3 cm in diameter, and
  • No evidence of vascular invasion or extrahepatic spread.

Related Terms

  • Hepatology: The branch of medicine that incorporates the study of liver, gallbladder, biliary tree, and pancreas as well as management of their disorders.
  • Hepatocellular carcinoma (HCC): A primary malignancy of the liver and occurs predominantly in patients with underlying chronic liver disease and cirrhosis.
  • Liver transplantation: A surgical procedure performed to replace a diseased liver with a healthy liver from another person.
  • Tumor: An abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function.
  • Vascular invasion: The spread of cancer cells into blood or lymph vessels.

External links

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