Mesulergine

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Mesulergine

Mesulergine (pronunciation: meh-suh-lur-geen) is a synthetic compound known for its psychoactive effects. It is often used in scientific research for its properties as a serotonin antagonist and a dopamine agonist.

Etymology

The term "Mesulergine" is derived from the combination of two words: "meso", which is Greek for "middle", and "ergine", which is a chemical compound found in several types of psychoactive fungi.

Pharmacology

Mesulergine acts as an antagonist at the 5-HT2A receptor, 5-HT2B receptor, and 5-HT2C receptor. It also acts as a partial agonist at the Dopamine receptor D4. The compound's psychoactive effects are primarily due to its action on these receptors.

Related Terms

  • Serotonin: A neurotransmitter that helps regulate mood, appetite, and sleep. It is the primary target of many antidepressant medications.
  • Dopamine: A neurotransmitter associated with pleasure and reward. It is often targeted in treatments for Parkinson's disease and schizophrenia.
  • 5-HT2A receptor: A subtype of the serotonin receptor that is a target of many psychedelic drugs.
  • 5-HT2B receptor: Another subtype of the serotonin receptor, which is involved in the regulation of mood and behavior.
  • 5-HT2C receptor: This subtype of the serotonin receptor is involved in the regulation of appetite and anxiety.
  • Dopamine receptor D4: A subtype of the dopamine receptor that is associated with novelty seeking behavior.

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