Martinostat
Martinostat
Martinostat (pronounced: Mar-ti-no-stat) is a small molecule inhibitor that is used in the field of epigenetics. It is specifically designed to target the enzymes known as histone deacetylases (HDACs).
Etymology
The term "Martinostat" is derived from the name of the scientist who first synthesized it, Dr. Martin, and the suffix "-stat", which is commonly used in pharmacology to denote substances that inhibit or stabilize a particular biological process or substance.
Usage
Martinostat is used in research to study the role of HDACs in various biological processes and diseases, including cancer, neurodegenerative diseases, and inflammatory diseases. By inhibiting the activity of HDACs, Martinostat can help to reveal the effects of these enzymes on gene expression and cell behavior.
Related Terms
- Epigenetics: The study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself.
- Histone deacetylases (HDACs): A class of enzymes that remove acetyl groups from an ε-N-acetyl lysine amino acid on a histone, allowing the histones to wrap the DNA more tightly.
- Cancer: A group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
- Neurodegenerative diseases: Diseases characterized by progressive nervous system dysfunction.
- Inflammatory diseases: Diseases characterized by inflammation, a response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants.
External links
- Medical encyclopedia article on Martinostat
- Wikipedia's article - Martinostat
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