Mammaglobin
Mammaglobin
Mammaglobin (/mæməˈɡloʊbɪn/), also known as MGB1, is a protein that in humans is encoded by the SCGB2A2 gene. It is a member of the uteroglobin family of secretoglobin proteins and is found primarily in the mammary gland.
Etymology
The term "mammaglobin" is derived from the Latin mamma meaning "breast" and the Greek globus meaning "ball" or "sphere". This refers to the protein's primary location in the mammary glands and its globular structure.
Function
Mammaglobin is a secreted protein that is highly expressed in human breast tissue and breast cancer cells. It is believed to play a role in the growth and development of breast tissue, as well as in the progression of breast cancer. However, the exact function of mammaglobin is still not fully understood.
Clinical significance
Due to its high expression in breast cancer cells, mammaglobin is often used as a biomarker for the detection and monitoring of breast cancer. It can be detected in the blood, urine, and tissue samples of patients with breast cancer, making it a useful tool for non-invasive cancer diagnosis and prognosis.
Related terms
External links
- Medical encyclopedia article on Mammaglobin
- Wikipedia's article - Mammaglobin
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