Low-molecular-weight heparin

Low-molecular-weight heparin (LMWH) is a class of anticoagulant medications. They are used in the prevention of blood clots and treatment of venous thromboembolism (VTE) and in myocardial infarction.

Pronunciation

Low-molecular-weight heparin is pronounced as loh-mo-lek-yuh-ler-weyt heh-puh-rin.

Etymology

The term "Low-molecular-weight heparin" is derived from its chemical structure. It is a smaller molecule than unfractionated heparin, hence the name "low molecular weight".

Usage

Low-molecular-weight heparins are used to prevent and treat deep vein thrombosis or pulmonary embolism, and serve as an alternative to heparin.

Mechanism of Action

Low-molecular-weight heparins inhibit thrombin and Factor Xa, two key proteins in the coagulation cascade, thereby preventing the formation of blood clots.

Related Terms

• Anticoagulant
• Blood clot
• Venous thromboembolism
• Myocardial infarction
• Heparin
• Thrombin
• Factor Xa

External links

• Medical encyclopedia article on Low-molecular-weight heparin
• Wikipedia's article - Low-molecular-weight heparin

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