Lipohyalinosis
Lipohyalinosis (pronunciation: li-po-hy-a-li-no-sis) is a medical term that refers to a specific type of small vessel disease in the brain. It is characterized by the thickening of the walls of small arterioles, leading to a reduction in blood flow and potentially causing a stroke.
Etymology
The term "Lipohyalinosis" is derived from three Greek words: "lipos" meaning fat, "hyalos" meaning glass, and "osis" meaning condition. Thus, it can be translated as a condition of fatty, glass-like deposits.
Pathogenesis
Lipohyalinosis is believed to be caused by chronic hypertension, which leads to damage to the small blood vessels in the brain. This damage results in the accumulation of a fatty, glass-like substance in the vessel walls, causing them to thicken and reduce blood flow.
Clinical Significance
Lipohyalinosis is a significant risk factor for lacunar stroke, a type of stroke that occurs when blood flow to one of the small arteries deep within the brain becomes blocked. It is also associated with cognitive impairment and dementia, particularly vascular dementia.
Related Terms
- Arteriole: A small branch of an artery leading into capillaries.
- Hypertension: A condition in which the force of the blood against the artery walls is too high.
- Stroke: A condition where the blood supply to part of the brain is reduced or interrupted, depriving brain tissue of oxygen and nutrients.
- Dementia: A group of thinking and social symptoms that interferes with daily functioning.
See Also
External links
- Medical encyclopedia article on Lipohyalinosis
- Wikipedia's article - Lipohyalinosis
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