Lacosamide
Lacosamide
Lacosamide (pronounced la-COS-a-mide) is an anticonvulsant medication used in the treatment of partial-onset seizures and diabetic neuropathic pain.
Etymology
The term "Lacosamide" is derived from the Latin word 'lac', meaning 'milk', and 'amide', a chemical functional group containing a carbonyl group (C=O) linked to a nitrogen atom. This is reflective of the drug's chemical structure.
Usage
Lacosamide is primarily used in the treatment of partial-onset seizures, a type of epilepsy where seizures begin in one part of the brain. It is also used to manage diabetic neuropathic pain, a type of nerve damage caused by diabetes.
Mechanism of Action
Lacosamide works by enhancing slow inactivation of voltage-gated sodium channels, which results in the stabilization of hyper-excitable neuronal membranes, inhibition of repetitive neuronal firing, and reduction of seizure propagation.
Side Effects
Common side effects of Lacosamide include dizziness, headache, nausea, and fatigue. Serious side effects may include suicidal thoughts, irregular heart rhythm, and severe allergic reactions.
Related Terms
- Anticonvulsant
- Partial-onset seizures
- Diabetic neuropathic pain
- Voltage-gated sodium channels
- Neuronal firing
- Seizure propagation
External links
- Medical encyclopedia article on Lacosamide
- Wikipedia's article - Lacosamide
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