Kyrle disease

Kyrle disease is a rare, acquired, perforating dermatosis that often presents as a chronic condition. It is characterized by hyperkeratotic papules and nodules, which are often found on the legs.

Pronunciation

Kyrle disease is pronounced as "Keer-lee disease".

Etymology

The disease is named after Ferdinand Kyrle, an Austrian dermatologist who first described the condition in 1916.

Symptoms

The primary symptom of Kyrle disease is the presence of large, hyperkeratotic papules and nodules. These are often found on the legs, but can also appear on the arms, trunk, and other parts of the body. The lesions may be itchy and can cause discomfort.

Causes

The exact cause of Kyrle disease is unknown. However, it is often associated with systemic conditions such as diabetes mellitus, renal disease, and liver disease. It has also been linked to certain medications, including hydrochlorothiazide and furosemide.

Diagnosis

Diagnosis of Kyrle disease is typically made through a combination of clinical examination and skin biopsy. The biopsy will show characteristic features of the disease, such as hyperkeratosis, parakeratosis, and transepidermal elimination of keratin and collagen.

Treatment

Treatment of Kyrle disease is primarily aimed at managing the underlying systemic condition. Topical treatments, such as keratolytics and corticosteroids, may also be used to help manage the skin lesions.

Related Terms

External links

Medical encyclopedia article on Kyrle disease
Wikipedia's article - Kyrle disease

This WikiMD dictionary article is a stub. You can help make it a full article.

Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski