KRAS
KRAS
KRAS (/kɹæs/), also known as Kirsten rat sarcoma viral oncogene homolog, is a protein that in humans is encoded by the KRAS gene. It is a member of the RAS gene family.
Pronunciation
The term KRAS is pronounced as "k-ras".
Etymology
The name KRAS is derived from the Kirsten rat sarcoma virus, which was where the gene was first identified. The term "oncogene" refers to a gene that has the potential to cause cancer, and "homolog" indicates that the gene is similar in structure and function to another gene.
Function
KRAS is a G protein that plays a crucial role in cell signal transduction. The protein product of the normal KRAS gene performs a crucial function in normal tissue signaling, and the mutation of a KRAS gene is an essential step in the development of many cancers.
Related Terms
See Also
References
External links
- Medical encyclopedia article on KRAS
- Wikipedia's article - KRAS
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