Jones' stain
Jones' Stain
Jones' Stain (pronounced: joʊnz steɪn) is a method of staining used in histology and pathology to detect certain structures in kidney tissues. The term is named after the pathologist Dr. Robert L. Jones who developed the technique.
Etymology
The term "Jones' Stain" is derived from the name of the pathologist Dr. Robert L. Jones who developed this staining technique. The word "stain" comes from the Old English word "stainan" which means to color or dye.
Description
Jones' Stain is a silver methenamine technique that is used primarily to stain renal biopsies. It is particularly useful in highlighting the basement membrane, mesangium, and glomerular capillary walls. This staining method is often used in the diagnosis of glomerulonephritis and other kidney diseases.
Procedure
The procedure for Jones' Stain involves several steps. First, the tissue sample is fixed and then sectioned. The sections are then stained with silver methenamine, which reacts with certain components of the tissue to produce a dark color. This allows the structures of interest to be clearly seen under a microscope.
Related Terms
- Histology: The study of the microscopic structure of tissues.
- Pathology: The study of disease, its causes, processes, development, and consequences.
- Basement Membrane: A thin, fibrous, extracellular matrix of tissue that separates the lining of an internal or external body surface from underlying connective tissue.
- Mesangium: A structure in the kidney that regulates blood flow in the glomerulus.
- Glomerulus: A network of tiny blood vessels in the kidney, where the filtration of blood takes place.
- Glomerulonephritis: A type of kidney disease in which the part of your kidneys that helps filter waste and fluids from the blood is damaged.
External links
- Medical encyclopedia article on Jones' stain
- Wikipedia's article - Jones' stain
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