Iofetamine (123I)
Iofetamine (123I)
Iofetamine (123I) (pronunciation: eye-oh-fet-a-meen) is a radiopharmaceutical used in nuclear medicine for the purpose of brain imaging. It is also known by its brand name, Neurolite.
Etymology
The term 'Iofetamine' is derived from the chemical compound it represents, which is a derivative of amphetamine. The '(123I)' denotes the presence of Iodine-123, a radioactive isotope of iodine, used in the compound for its radiotracer properties.
Usage
Iofetamine (123I) is primarily used in Single Photon Emission Computed Tomography (SPECT) scans of the brain. It helps in the detection of abnormalities in the brain, such as those seen in strokes, dementia, and other neurological disorders.
Mechanism of Action
Iofetamine (123I) works by binding to the norepinephrine transporter in the brain. After injection, it is taken up by the brain tissue and its distribution is imaged using a gamma camera. This allows for the visualization of blood flow and metabolism in the brain.
Related Terms
- Radiopharmaceutical
- Nuclear medicine
- Brain imaging
- Amphetamine
- Iodine-123
- Single Photon Emission Computed Tomography
- Stroke
- Dementia
- Neurological disorders
- Norepinephrine
- Gamma camera
External links
- Medical encyclopedia article on Iofetamine (123I)
- Wikipedia's article - Iofetamine (123I)
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