Intermediate trophoblast
Intermediate trophoblast
Intermediate trophoblast (pronunciation: in-ter-mee-dee-ate trof-o-blast) is a type of trophoblast that is part of the placenta in mammals, including humans. It is involved in the implantation of the embryo and the formation of the placental barrier, which regulates the exchange of substances between the mother and the fetus.
Etymology
The term "intermediate trophoblast" is derived from the Greek words "trophos" (nourishment) and "blastos" (germ), indicating its role in providing nourishment to the developing embryo. The prefix "intermediate" refers to its position between the other two types of trophoblasts, the cytotrophoblast and the syncytiotrophoblast.
Function
The intermediate trophoblast is responsible for the invasion of the maternal endometrium (the lining of the uterus), a process that is crucial for the establishment of the placenta and the successful progression of pregnancy. It also contributes to the formation of the extravillous trophoblast, which is involved in the remodeling of maternal spiral arteries to ensure adequate blood flow to the placenta.
Related terms
- Trophoblast: The outer layer of cells in a mammalian blastocyst that provides nutrients to the embryo and develops into a large part of the placenta.
- Cytotrophoblast: The inner layer of the trophoblast, which forms the wall of the blastocyst and provides cells for the formation of the placenta.
- Syncytiotrophoblast: The outer layer of the trophoblast, which forms the embryonic part of the placenta and is involved in the exchange of gases and nutrients between the mother and the fetus.
- Extravillous trophoblast: A subtype of trophoblast that invades the maternal endometrium and remodels the spiral arteries.
External links
- Medical encyclopedia article on Intermediate trophoblast
- Wikipedia's article - Intermediate trophoblast
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