Inotrope
Inotrope
Inotrope (pronounced: /ˈaɪnəˌtroʊp/) is a term used in medicine to describe a class of drugs that alter the force or energy of muscular contractions. Negatively inotropic agents weaken the force of muscular contractions. Positively inotropic agents increase the strength of muscular contraction.
Etymology
The term "inotrope" comes from the Greek words "ino" meaning fibre and "tropos" meaning a turning. It refers to the effect these drugs have on the force of heart muscle contraction.
Types of Inotropes
There are two main types of inotropes: Positive inotropes and Negative inotropes.
- Positive inotropes increase the force of the heart's contractions, allowing it to pump more blood. Examples include Digoxin and Dobutamine.
- Negative inotropes decrease the force of the heart's contractions and slow the heart rate. Examples include Beta blockers and Calcium channel blockers.
Related Terms
- Chronotrope: A drug that changes the heart rate.
- Dromotrope: A drug that changes the speed of electrical conduction in the heart.
- Lusitrope: A drug that changes the rate of relaxation of the heart muscle.
See Also
External links
- Medical encyclopedia article on Inotrope
- Wikipedia's article - Inotrope
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