Indirect pathway
Indirect Pathway
The Indirect Pathway (pronunciation: /ɪnˈdaɪrɛkt ˈpæθweɪ/) is a significant component of the Basal Ganglia circuitry in the human brain. It is also known as the extrapyramidal indirect pathway.
Etymology
The term "Indirect Pathway" is derived from its function in the neurological system. It is called "indirect" because it involves more synapses than the direct pathway, thus taking a more "indirect" route.
Function
The Indirect Pathway functions to inhibit movements. It is a part of the motor system and works in opposition to the direct pathway. The Indirect Pathway starts in the striatum, passes through the globus pallidus externus (GPe) and the subthalamic nucleus (STN), and ends in the globus pallidus internus (GPi) and substantia nigra pars reticulata (SNr).
Related Terms
- Basal Ganglia: A group of nuclei in the brain associated with a variety of functions including control of voluntary motor movements.
- Direct Pathway: A neural pathway in the brain that facilitates movement, working in conjunction with the Indirect Pathway.
- Striatum: A part of the brain involved in the reward system and movement.
- Globus Pallidus: A subcortical structure of the brain involved in the regulation of voluntary movement.
- Subthalamic Nucleus: A small lens-shaped nucleus in the brain where it is, together with the substantia nigra, part of the subthalamus.
- Substantia Nigra: A basal ganglia structure located in the midbrain that plays an important role in reward and movement.
External links
- Medical encyclopedia article on Indirect pathway
- Wikipedia's article - Indirect pathway
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