Imipramine
Imipramine
Imipramine (pronounced as im-ip-ra-meen) is a type of medication that belongs to the class of drugs known as tricyclic antidepressants (TCAs). It is primarily used in the treatment of depression and enuresis (involuntary urination).
Etymology
The term "Imipramine" is derived from its chemical name, 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine. It was the first tricyclic antidepressant to be developed, in the 1950s.
Usage
Imipramine is used to treat symptoms of depression such as feelings of sadness, worthlessness or guilt, loss of interest in daily activities, insomnia, fatigue, and suicidal thoughts. It is also used in the treatment of enuresis in children.
Mechanism of Action
Imipramine works by increasing the levels of certain natural substances in the brain (norepinephrine and serotonin) that help elevate mood and reduce the symptoms of depression.
Side Effects
Common side effects of Imipramine include dry mouth, blurred vision, constipation, weight gain, dizziness, and increased heart rate. Severe side effects may include suicidal thoughts, chest pain, rapid or irregular heartbeat, and severe nausea or vomiting.
Related Terms
External links
- Medical encyclopedia article on Imipramine
- Wikipedia's article - Imipramine
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