Idiotopes
Idiotopes
Idiotopes (pronunciation: /ˈɪdiəˌtoʊp/) are unique antigenic determinants that are found on the variable region of an antibody molecule. They are responsible for the specificity of the antibody for its corresponding antigen.
Etymology
The term "idiotope" is derived from the Greek words "idios" meaning "own, private, separate" and "topos" meaning "place". It was first used in the field of immunology in the 1970s to describe the unique antigenic determinants on an antibody molecule.
Related Terms
- Antibody: A protein produced by the body's immune system when it detects harmful substances, called antigens.
- Antigen: A substance that induces an immune response in the body, especially the production of antibodies.
- Immunoglobulin: Another term for an antibody. There are several different types of immunoglobulins, each of which has a different role in the immune response.
- Epitope: The part of an antigen molecule to which an antibody attaches itself.
- Paratope: The part of an antibody which recognizes and binds to an antigen.
See Also
External links
- Medical encyclopedia article on Idiotopes
- Wikipedia's article - Idiotopes
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