Idecabtagen-Viceucel

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Idecabtagen-Viceucel
TermIdecabtagen-Viceucel
Short definitionIdecabtagen-Viceucel (I-deh-KAB-tuh-jeen vik-LOO-sel) A drug used to treat adults with multiple myeloma who have been treated with at least four other cancer therapies, including an anti-CD38 monoclonal antibody, a proteasome inhibitor, and an immunomodulating agent, relapsed (come back) or did not improve. It is also being studied in the treatment of other types of cancer. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


Idecabtagen-Viceucel - (pronounced) (I-deh-KAB-tuh-jeen vik-LOO-sel) A drug used to treat adults with multiple myeloma who have been treated with at least four other cancer therapies, including an anti-CD38 monoclonal antibody, a proteasome inhibitor, and an immunomodulating agent, relapsed (come back) or did not improve. It is also being studied in the treatment of other types of cancer. Idecabtagene-Viceucel is made using a patient's T cells (a type of cell in the immune system). A gene for a special receptor called the chimeric antigen receptor (CAR) is added to the T cells in the laboratory. Large numbers of these modified T cells, known as CAR T cells, are cultivated in the laboratory and given to the patient by infusion. Idecabtagene-Vicleucel attaches to a protein called BCMA, which is found on myeloma cells and some types of immune cells. This helps the body's immune system kill cancer cells. Idecabtagene Vicleucel is a type of CAR T cell therapy. Also called Abecma

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