Hydroxycarbamide
Hydroxycarbamide
Hydroxycarbamide (pronounced: hy·droxy·car·ba·mide), also known as hydroxyurea, is a medication primarily used in the treatment of cancer and certain blood disorders.
Etymology
The term "hydroxycarbamide" is derived from its chemical structure, which includes a hydroxyl group (-OH) and a carbamide (or urea) moiety.
Usage
Hydroxycarbamide is used in the treatment of several types of cancer, including chronic myeloid leukemia, ovarian cancer, and certain types of skin cancer. It is also used to manage sickle cell disease, reducing the frequency of painful crises and the need for blood transfusions in people with this condition.
Mechanism of Action
Hydroxycarbamide works by inhibiting an enzyme called ribonucleotide reductase, which is crucial for DNA synthesis. By blocking this enzyme, the drug slows down the growth of cancer cells.
Side Effects
Common side effects of hydroxycarbamide include nausea, vomiting, diarrhea, and loss of appetite. More serious side effects may include bone marrow suppression, leading to a decrease in blood cell counts.
Related Terms
External links
- Medical encyclopedia article on Hydroxycarbamide
- Wikipedia's article - Hydroxycarbamide
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