Heiko Braak
Heiko Braak
Heiko Braak (pronounced: Hei-ko Bra-ak) is a renowned German neuroanatomist and neuropathologist, best known for his work on the pathological staging of neurodegenerative diseases, particularly Parkinson's disease and Alzheimer's disease.
Etymology
The name "Heiko" is of German origin and means "home ruler". "Braak" is a Dutch surname, which means "fallow" or "uncultivated".
Biography
Heiko Braak was born in Germany and completed his medical studies at the University of Hamburg. He is known for his extensive research in the field of neuropathology, with a focus on neurodegenerative diseases. His work has significantly contributed to the understanding of the progression and staging of diseases such as Parkinson's and Alzheimer's.
Braak Staging
Braak's most notable contribution to the field of neuropathology is the development of the Braak Staging, a system used to classify the progression of Alzheimer's disease and Parkinson's disease based on the extent of tau protein and alpha-synuclein pathology. This system has been widely adopted in neuropathological research and clinical practice.
Related Terms
- Neurodegenerative diseases: A variety of medical conditions characterized by the progressive degeneration and death of nerve cells. This includes diseases such as Alzheimer's and Parkinson's.
- Parkinson's disease: A long-term degenerative disorder of the nervous system that mainly affects the motor system.
- Alzheimer's disease: A chronic neurodegenerative disease that usually starts slowly and gradually worsens over time. It is the cause of 60–70% of cases of dementia.
- Braak Staging: A system developed by Heiko Braak used to classify the progression of Alzheimer's disease and Parkinson's disease.
- Tau protein: A protein that stabilizes microtubules. It is abundant in neurons of the central nervous system and is often defective in neurodegenerative diseases.
- Alpha-synuclein: A protein that, in humans, is encoded by the SNCA gene. It is abundant in the brain and is associated with neurodegenerative diseases.
External links
- Medical encyclopedia article on Heiko Braak
- Wikipedia's article - Heiko Braak
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