HMOX1
HMOX1
HMOX1 (pronounced as "H-M-O-X-One"), also known as Heme Oxygenase 1, is a human gene that encodes the enzyme heme oxygenase 1. This enzyme is part of the heme oxygenase system, which is responsible for the degradation of heme, a component of hemoglobin.
Etymology
The term "HMOX1" is an abbreviation of Heme Oxygenase 1. "Heme" is derived from the Greek word "haima", meaning blood. "Oxygenase" refers to the class of enzymes that catalyze the incorporation of oxygen into organic compounds.
Function
The enzyme encoded by the HMOX1 gene is responsible for the oxidative cleavage of heme, producing biliverdin, iron, and carbon monoxide. This process is critical for the body's iron recycling process and the regulation of cellular response to oxidative stress.
Related Terms
- Heme: A component of hemoglobin, which is broken down by the enzyme heme oxygenase 1.
- Enzyme: A protein that catalyzes a specific biochemical reaction.
- Heme Oxygenase: The system responsible for the degradation of heme.
- Biliverdin: A green tetrapyrrolic bile pigment, and is a product of heme catabolism.
- Oxidative Stress: An imbalance between the production of free radicals and the ability of the body to counteract or detoxify their harmful effects through neutralization by antioxidants.
External links
- Medical encyclopedia article on HMOX1
- Wikipedia's article - HMOX1
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