Glucocorticoid receptor

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Glucocorticoid receptor

The Glucocorticoid receptor (pronounced: gloo-ko-KOR-ti-koid re-SEP-tor), often abbreviated as GR, is a type of protein that is found inside cells and acts as a receptor for glucocorticoids.

Etymology

The term "Glucocorticoid receptor" is derived from the words "gluco", referring to glucose, "corticoid", referring to the cortex of the adrenal gland where glucocorticoids are produced, and "receptor", which refers to a protein that binds to specific molecules.

Function

The Glucocorticoid receptor binds to glucocorticoids, which are a type of steroid hormone that is involved in the regulation of metabolism and immune response. When a glucocorticoid binds to the receptor, it causes a change in the shape of the receptor, allowing it to move into the cell's nucleus and influence the expression of certain genes.

Related Terms

  • Glucocorticoids: A type of steroid hormone that regulates a wide range of processes in the body, including metabolism and immune response.
  • Adrenal gland: A small gland located on top of each kidney. They produce hormones including glucocorticoids.
  • Protein: A large molecule composed of one or more chains of amino acids in a specific order. Proteins are necessary for the structure, function, and regulation of the body's cells, tissues, and organs.
  • Steroid hormone: A type of hormone that is lipid-soluble and can pass through cell membranes to influence gene expression.

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