Glecaprevir; pibrentasvir
Glecaprevir; Pibrentasvir
Glecaprevir; Pibrentasvir (pronunciation: gleh-KAP-reh-veer; pih-BREN-tas-veer) is a combination medication used in the treatment of Hepatitis C.
Etymology
The names 'Glecaprevir' and 'Pibrentasvir' are derived from the chemical structures of the two active substances. The '-previr' suffix in Glecaprevir is common in antiviral medications, particularly those targeting HCV. The '-asvir' suffix in Pibrentasvir is also common in antiviral medications, specifically those that inhibit the NS5A protein of the HCV.
Usage
Glecaprevir; Pibrentasvir is used to treat all six major forms of HCV, including both acute and chronic forms. It is particularly effective in treating patients who have not responded to other treatments.
Mechanism of Action
Glecaprevir is a protease inhibitor, which works by blocking the action of an enzyme that the HCV uses to replicate. Pibrentasvir is an NS5A inhibitor, which works by interfering with a protein the virus needs to assemble itself. Together, they prevent the virus from multiplying and can reduce the amount of HCV in the body.
Related Terms
See Also
External links
- Medical encyclopedia article on Glecaprevir; pibrentasvir
- Wikipedia's article - Glecaprevir; pibrentasvir
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