Gleason grading system
Gleason Grading System
The Gleason Grading System (pronunciation: /ˈgliːsən/) is a histological grading system used to evaluate the prognosis of men with prostate cancer. It was developed by Donald Floyd Gleason in the 1960s.
Etymology
The system is named after its creator, Donald Floyd Gleason, a pathologist at the Minneapolis Veterans Affairs Medical Center.
Description
The Gleason Grading System is based on the architectural pattern of prostate cancer cells in biopsy samples. It assigns a grade from 1 to 5, with 1 being the least aggressive and 5 being the most aggressive. The grades are then combined to give a Gleason score, which can range from 2 to 10. The higher the Gleason score, the more likely the cancer is to grow and spread quickly.
Related Terms
- Prostate Cancer: A type of cancer that occurs in the prostate, a small walnut-shaped gland in men that produces the seminal fluid that nourishes and transports sperm.
- Histology: The study of the microscopic structure of tissues.
- Biopsy: A procedure that involves taking a small sample of tissue for examination under a microscope.
- Prognosis: The likely course of a disease or ailment.
- Donald Floyd Gleason: An American pathologist who developed the Gleason Grading System.
See Also
External links
- Medical encyclopedia article on Gleason grading system
- Wikipedia's article - Gleason grading system
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