Factor Va

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Factor Va

Factor Va (pronounced as "factor five a") is a coagulation factor that plays a crucial role in the blood clotting process. It is an activated form of Factor V, a larger protein that is cleaved to produce Factor Va and Factor Vb.

Etymology

The term "Factor Va" originates from the Latin word "factor", meaning "maker" or "doer", and the Roman numeral "V", which stands for 5, followed by the lowercase "a". This nomenclature is used to denote the activated form of Factor V.

Function

Factor Va serves as a cofactor for Factor Xa in the conversion of prothrombin to thrombin, a key enzyme in the coagulation cascade. This process is essential for the formation of a stable blood clot following vascular injury.

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